{"id":12520,"date":"2022-02-09T07:31:54","date_gmt":"2022-02-09T07:31:54","guid":{"rendered":"http:\/\/drsertus.uz\/?post_type=product&p=12520"},"modified":"2022-02-28T12:33:13","modified_gmt":"2022-02-28T12:33:13","slug":"lekoksa","status":"publish","type":"product","link":"http:\/\/drsertus.uz\/uz\/mahsulot\/lekoksa\/","title":{"rendered":"Lekoksa"},"content":{"rendered":"

FARMAKOLOGIK GURUH
\n<\/strong>Steroid bo'lmagan yallig'lanishga qarshi vosita.<\/p>\n

DORI NOMI
\n<\/strong>Lekoksa<\/p>\n

<\/strong>TARKIBI
\n<\/strong>Selekoksib 200 mg<\/p>\n

FOYDALANISH UCHUN KO\u2018RSATMALAR\u00a0<\/strong>\u00a0<\/strong><\/p>\n

Simptomatik davolash sifatida:<\/p>\n

- artrit (Romatoid artrit, osteoartrit), spondilit;<\/p>\n

- algodismenore;<\/p>\n

- o'tkir og'riq.<\/p>\n

Adenomatoz kolorektal poliplar soni va hajmini kamaytirish uchun oilaviy adenomatoz polipozli bemorlar uchun kompleks terapiyaning bir qismi sifatida.<\/p>\n

QO'LLANISH TARTIBI VA DOZALARI\u00a0<\/strong><\/p>\n

Lekoks preparati ovqatdan qat'i nazar, og'iz orqali qo'llaniladi.<\/p>\n

Tavsiya etilgan sutkalik doza 200 mg ni tashkil qiladi.kuniga bir marta 200 mg va kuniga 2 marta 100 mg dan foydalanish mumkin. Agar kerak bo'lsa, preparatning dozasi istalmagan reaktsiyalarni rivojlanish xavfini oshirmasdan kuniga 400 mg gacha (kuniga 2 marta 200 mg) oshirilishi mumkin.<\/p>\n

Yurak-qon tomir tizimining asoratlari selekoksib dozasiga bog'liqligini hisobga olib, preparatni minimal samarali dozalarda, qisqa muddatli kurslarda qo'llash kerak.<\/p>\n

CHILISh FORMASI
\n<\/strong>Kaps\u00fcller \u2116 30<\/p>\n

FARMAKOLOGIK XUSUSIYATLARI<\/strong><\/p>\n

Lekoks-NSAID, giyohvand bo'lmagan analjezik, og'iz orqali qabul qilish uchun og'riq qoldiruvchi vosita.<\/p>\n

Selekoksibning ta'sir qilish mexanizmi siklooksigenaza-2 (Cox-2) faolligini imtiyozli ravishda bostirish va Cox-1 ni minimal bostirishdan iborat. Cox-2 ning faollashishi yallig'lanish tufayli biologik faol moddalarning chiqarilishiga javoban sodir bo'ladi.<\/p>\n

Lekoka og'riq qoldiruvchi, antipiretik va yallig'lanishga qarshi ta'sirga ega.<\/p>\n

QO'SHILMALARI<\/strong><\/p>\n

- selekoksib yoki preparatning boshqa tarkibiy qismlariga yuqori sezuvchanlik;<\/p>\n

- o'tkir bosqichda oshqozon yarasi yoki oshqozon-ichakdan qon ketish;<\/p>\n

- yurak etishmovchiligi (NYHAII-IV);<\/p>\n

- og'ir jigar va buyrak etishmovchiligi (foydalanish tajribasi yo'q).<\/p>\n

\u00a0<\/strong><\/p>\n

YON EFFEKTLAR<\/strong><\/p>\n

Yurak-qon tomir tizimi tomonidan: periferik shish.<\/p>\n

Oshqozon-ichak traktidan: qorin og'rig'i, diareya, dispepsiya, meteorizm.<\/p>\n

Asab tizimidan: bosh aylanishi, mushaklarning kuchayishi, uyqusizlik.<\/p>\n

Teri tomondan: terining qichishi, teri toshmasi.<\/p>\n

 <\/p>\n

BOSHQA DORILAR BILAN O\u2018ZBARCHA TA\u2019SIRI<\/strong><\/p>\n

Varfarin bilan bir vaqtda qo'llash natijasida qon ketish xavfi o'limga olib kelishi mumkin.<\/p>\n

Flukonazol va ketokonazol bilan bir vaqtda yuborilganda qondagi selekoksib kontsentratsiyasi ikki baravar ko'payishi mumkin.<\/p>\n

ANGIOTENSINNI o'zgartiradigan ferment inhibit\u00f6rleri yoki NSAID bilan angiotensin II blokerlari buyurilganda, ularning antihipertenziv ta'siri kamayishi mumkin.<\/p>\n

MAXSUS KO'RSATMALAR<\/strong><\/p>\n

Lekoks preparatini qabul qilishda tromboz, shu jumladan hayotiy organlarda (yurak va miya) rivojlanish xavfi ortishi mumkin, shuning uchun iloji bo'lsa, terapiya qisqa vaqt ichida minimal samarali dozalarda o'tkazilishi kerak.<\/p>\n

Oshqozon va o'n ikki barmoqli ichak yarasi keksa bemorlarda, oshqozon yarasi tarixi bo'lgan bemorlarda, zaiflashgan bemorlarda, Asetilsalitsil kislotasi bilan bir vaqtda qabul qilinganda tez-tez uchraydi.<\/p>\n

Preparat surunkali yurak etishmovchiligi bo'lgan bemorlarga ehtiyotkorlik bilan buyuriladi, chunki suyuqlikni ushlab turish va periferik shish paydo bo'lishi mumkin.\u00a0 \u00a0 \u00a0 \u00a0 \u00a0 \u00a0 \u00a0 \u00a0 \u00a0 \u00a0 \u00a0 \u00a0 \u00a0 \u00a0 \u00a0 <\/strong><\/p>","protected":false},"excerpt":{"rendered":"

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